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J Korean Soc Emerg Med > Volume 21(3); 2010 > Article
Journal of The Korean Society of Emergency Medicine 2010;21(3): 412-415.
Acute Fatty Liver of Pregnancy Associated with Diabetes Insipidus
Jung Soo Park, Hoon Kim, Suk Woo Lee
Department of Emergency Medicine, College of Medicine, Chungbuk National University, Cheongju, Korea. drrhec@chungbuk.ac.kr
Acute fatty liver of pregnancy (AFLP) is a rare but potentially fatal complication of pregnancy that occurs in the third trimester, and results in microvesicular fat deposition in the liver, resulting in severe hepatic dysfunction. AFLP diagnosis is very difficult because of the low sensitivity of noninvasive radiologic techniques including ultrasound, computed tomography, and magnetic resonance imaging. Hence, one has to take a careful history and do a careful physical examination with laboratory finding for diagnosis of AFLP. Prompt diagnosis and early delivery can greatly decrease maternal and perinatal mortality.
Key words: Fatty liver, Pregnancy, Free fatty acids
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