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J Korean Soc Emerg Med > Volume 23(6); 2012 > Article
Journal of The Korean Society of Emergency Medicine 2012;23(6): 825-830.
The Prognostic Abilities of Severity Scoring Systems for Patients with Septic Shock
Hyoung Ju Lee, Tae Nyoung Chung, Jae Young Lee, Jin Kun Bae, Eui Chung Kim, Sung Wook Choi, Ok Jun Kim, Yun Kyung Cho
1Department of Emergency Medicine, CHA Bundang Medical Center, CHA University, Seongnam, Korea. hendrix74@cha.ac.kr
2Department of Internal Medicine, CHA Gangnam Medical Center, CHA University, Seongnam, Korea.
The aim of the study was to validate abbreviated mortality in emergency department sepsis (MEDS) scoring system by comparing it with original MEDS score and to assess the prognostic value of other prognostic factor for sepsis patients including multiple organ dysfunction score (MODS), sepsis-related organ failure assessment (SOFA) score, and serum procalcitonin level.
Adult patients visiting emergency department (ED) with evidence of septic shock were enrolled to the study. MEDS score, MODS, and SOFA score were calculated based on initial clinical data. Receiver-operating characteristics (ROC) analyses were used to assess the prognostic factors for predicting mortality. Kaplan-Meier survival analyses (KMSA) were used to determine whether the prognostic factors had correlation with survival time.
Only MODS showed significant predicting power for mortality (p=0.003, area under curve=0.625). Estimated median survival of all the patients calculated by KMSA was 11.0 (standard error 1.7) days, and predefined criteria of all prognostic factors showed significant differences in survival time.
MEDS, abbreviated MEDS, MODS, and SOFA scoring systems were useful factors for predicting survival time of septic shock patients visiting ED.
Key words: Septic shock, Prognosis, Survival, MEDS
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