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J Korean Soc Emerg Med > Volume 32(5); 2021 > Article
Journal of The Korean Society of Emergency Medicine 2021;32(5): 394-399.
응급실을 내원한 요관결석 환자에서 크기가 5 mm 이상인 집단과 5 mm 미만인 집단 간의 임상적 특성과 neutrophil-lymphocyte ratio, platelet lymphocyte ratio, C-reactive protein의 비교
정원동1 , 최우익1 , 정원호2 , 박동진3 , 서영진3 , 이경섭3 , 전재천1
1계명대학교 의과대학 응급의학교실
2계명대학교 의과대학 비뇨의학교실
3동국대학교 의과대학 비뇨의학교실
Correlation between the size of the ureter stone and the neutrophil-lymphocyte ratio, platelet lymphocyte ratio, and C-reactive protein in patients with ureter stone visiting the emergency department
Won Dong Jeong1 , Woo-Ik Choi1 , Wonho Jung2 , Dong Jin Park3 , Young Jin Seo3 , Kyung Seop Lee3 , Jae Cheon Jeon1
1Department of Emergency Medicine, University of Keimyung College of Medicine, Daegu, Korea
2Department of Urology, University of Keimyung College of Medicine, Daegu, Korea
3Department of Urology, Dongguk University College of Medicine, Gyeongju, Korea
Correspondence  Jae Cheon Jeon ,Tel: 053-258-7896, Fax: 053-258-6305, Email: cheon9803@naver.com,
Received: July 9, 2020; Revised: August 26, 2020   Accepted: September 25, 2020.  Published online: October 31, 2021.
ABSTRACT
Objective:
The size and location of ureter stones are important factors in their spontaneous passage. We compared the clinical characteristics and neutrophil-lymphocyte ratio (NLR), platelet lymphocyte ratio (PLR), and C-reactive protein (CRP) of patients who visited the emergency department with ureter stones of ≥5 mm and <5 mm in size.
Method:
We retrospectively reviewed 699 patients who visited the emergency department of two medical centers from January 2017 to December 2019. We compared microscopic hematuria, pyuria, NLR, PLR, CRP, the grade of hydronephrosis, and the location of ureteral calculi between the two groups.
Results:
There were 419 patients with ureter stones less than 5 mm and 280 patients with stones more than 5 mm in size. NLR was 2.82 (1.44-4.73) and 3.12 (1.94-5.75) in patients with stones <5 mm and ≥5 mm, respectively (P=0.001). PLR was 117.2 (88.2-164.9) and 136.0 (98.9-199.7) in patients with stones <5 mm and ≥5 mm, respectively (P=0.001). CRP was 0.29 (0.29-0.29) and 0.29 (0.29-1.04) in patients with stones <5 mm and ≥5 mm, respectively (P<0.001). The proportion of microscopic hematuria was 84.7% and 76.4% in patients with stones <5 mm and ≥5 mm, respectively (P=0.006). The proportion of pyuria was 20.5% and 41.8% in patients with stones <5 mm and ≥5 mm, respectively (P=0.01).
Conclusion:
In patients with ureter stones ≥5 mm, CRP, NLR, and PLR were significantly higher than patients with ureter stones <5 mm. However, further studies are needed before using these indicators to make clinical decisions regarding ureteral stone management.
Key words: Ureteral calculi; Neutrophil-to-lymphocyte ratio; Platelet-to-lymphocyte ratio; C-reactive protein
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