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J Korean Soc Emerg Med > Volume 7(3); 1996 > Article
Journal of The Korean Society of Emergency Medicine 1996;7(3): 345-353.
PaCO2 AND RETURN OF SPONTANEOUS CIRCULATION DURING CARDIOPULMONARY RESUSCITATION
Jong Kwon Park, Yeo Kyu Youn
1Department of Emergency Medicine, Seoul National University College of Medicine, Seoul, Korea
2Department of Surgery, Seoul National University College of Medicine, Seoul, Korea
  Published online: September 30, 1996.
ABSTRACT
Despite significant laboratory and clinical research on cardiac arrest and cardiopulmonary resusci­tation, there has been a minimal effect on resuscitation rates. Several large hospitals have reported ROSC(return of spontaneous circulation) rates of only 1% to 2% or 10% in its maximal rate. Many efforts to evaluate the factors that represent the efficacy of treatment and prognosis have been made. End-tidal CO2, acid base status, venous oxygen saturation and many kind of animal experiments have been performed and analysed. But most of the factors has its usefulness and limitation During cardiopulmonary resuscitation, simple and clinically available prognostic factors are needed. PaCO2 as a nonspocific clinical prognostic factor is related to the cardiac output and subsequent clinical outcome. The less the PaCO2 value, the better the rate of ROSC. In fact the patients with PaCO2 less than 35mmHg had 5 to 6 times better rates of ROSC than the ones with more than 45mmHg. During the 17 months of period, 372 patients with cardiac arrest have been resuscitated at the emergency room of Seoul National University Hospital. Among many factors only PaCO2 is related to the rate of ROSC(return of spontaneous circulation) and statistically significant.
Key words: ROSC, PaCO2 , Cardiopulmonary resuscitation
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