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J Korean Soc Emerg Med > Volume 6(1); 1995 > Article
Journal of The Korean Society of Emergency Medicine 1995;6(1): 176-183.
A CLINICAL STUDY OF ACUTE CARBON MONOXIDE POISONING
Moon Hwan Kim
Emergency Center, Jang Sung Hospital
  Published online: June 30, 1995.
ABSTRACT
We experienced two hundred sixty six patients of acute carbon monoxide poisoning admitted to Jang Sung hospital through emergency center from January 1987 to December 1994, and they were clinically analyzed and evaluated including delayed postanoxic encephalopathy. Mean age of the patients was 38.7 土18.3 years and the ratio of male to female was 1: 1.5. Mental state was alert mostly(50.7%), and their chief complaints were headache, nausea, and dizzi­ness. The more disturbed mental state, the more decreased arterial pH and PaC02, which may be the result of metabolic acidosis. The early laboratory findings in patients were ; Ieukocytosis 57.5%, increased hematocrit 23.3%, hyperglycemia 18%, increased GPT 14.7%, increased BUN 5.3%, glucosuria 19.2%, and proteinuria 12.0%. The abnormal electrocardiography findings(24.8% of 266 cases) were sinus tachycardia, T wave inversion, sinus bradycardia, ST T change, tall T wave( >10mm), low voltage and incomplete RBBB with incidence and thir­teen cases have two or more abnormal findings. The incidence of delayed postanoxic encephalopathy was 6.0 % and two cases died in the period of admission because of multiorgan failure and respiratory failure in each cases. We concluded that initial treatment of the carbon monoxide poisoned patient who cardiopul­monary function was preserved are hyperbaric oxygen therapy and conservative management of cerebral edema. Therefore, we suspect good clinical result and prognosis even in coma patients.
Key words: Acute carbon monoxide poisoning, Delayed postanoxic encephalopathy
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