| TWO CASES OF TRAUMATIC RHABDOMYOLYSIS WITH ACUTE RENAL FAILURE |
| Ok Kyung Choi, In Cheol Park, Seok Joon Jang, Seung Ho Kim |
| Department of Emergency Medicine, Severance Hospital, Yonsei University College of Medicine |
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Published online: July 31, 1994. |
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| ABSTRACT |
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Rhabdomyolysis may be defined as a reversible or irreversible skeletal muscle injury with release of muscle cell contents into the plasma. The classic description of rhabdomyolysis presented by Bywater and Beall in 1941 includes the clinical presentation of traumatic skeletal muscle injury, pigmented urine and acute renal failure. The major clinical and fatal sequalae of rhabdomyolysis is associated with acute renal failure. Therefore, early recognition and prompt management are essential. We feel that a lack of familiality with the syndrome may contribute to delay in diagnosis and treatment and reduce the chances for functional neuromuscular recovery.
We report 2 cases demonstrating acute renal failure associated with traumatic rhabdomyolysis. A 65-year old male and a 36-year old female patient were admitted to our Department of Emergency Medicine because of pain and swelling in lower extremities as a result of mild trauma. Metabolic features including hyperkalemia, hypercalcemia, hyperphosphatemia, hyperuricemia and coagulation defect were present in both patients and
acute renal failure with myoglobinuria has developed. In male patient peritoneal dialysis was initiated. On the 40th hospital day, he was discharged, having regained virtually normal renal function. The female patient was treated with conservative manner and was discharged with normal renal function on the 30th hospital day.
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| Key words:
rhabdomyolysis, acute renal failure |
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