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Journal of The Korean Society of Emergency Medicine 2001;12(4): 536-540. |
| A Case of Primary Central Nervous System Lymphoma with Panhypopituitarism |
| Won Young Kim, Won Kim, Gyu Chong Cho, Jung Suck Hong, Mi Woo Lee, Sung Eun Jang, Se Hyun Oh, Kyoung Soo Lim |
1Department of Emergency Medicine, University of Ulsan College of Medicine, Asan Medical Center, Korea. wonpia@yahoo.co.kr
2Department of Dermatology, University of Ulsan College of Medicine, Asan Medical Center, Korea.
3Department of Emergency Medicine, Kangnung Hospital, Korea. |
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| ABSTRACT |
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A primary central nervous system lymphoma(PCNSL) is defined as a lymphoma limited to the cranialspinal axis without systemic involvement. PCNSLs were formerly very rare, only 0.5~1.2% of all intracranial neoplasms, and were usually associated with acquired immuno-deficiency syndrome(AIDS) and other immuno-compromised states. Recently, there has been a clear rise in the incidence of this disease among normal individuals. We describe a 77-year-old female with hyponatremia who presented with a confused mental state.
Computed tomography(CT) of the brain demonstrated a suprasellar mass with enhancement. We evaluated the basic hormonal studies and the magnetic resonance imaging(MRI). A ventricular biopsy was done, and the result was a diffuse, large, B-cell-type malignant lymphoma. She presented panhypopituitarism and partial central diabetes insipidus.
She received chemotheraphy and was discharged in an improved condition. We report a case of panhypopituitarism due to PCNSL and give a review of the literature. |
| Key words:
Primary central nervous system lymphoma, Panhypopituitarism |
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