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J Korean Soc Emerg Med > Volume 13(1); 2002 > Article
Journal of The Korean Society of Emergency Medicine 2002;13(1): 106-109.
Case Report of Tetanus Which is Treated by Human Tetanus Immunoglobulin 500 Unit
Soo Hyeong Cho, Nam Soo Cho, Meung Ryong Kim, Sin Ju
Department of Emergency Medicine, Chosun University Hospital, Kwangju, Korea. nschoer@hanmail.net
ABSTRACT
Tetanus is a neurologic disorder, characterized by increased muscle tone and spasms, that is caused by tetanospasmin, a powerful protein toxin elaborated by Clostridium tetani. In the modern society, tetanus is a rare disease, but it has a high mortality on attack and it 's diagnosis depends on the clinical symptoms. The treatment for tetanus is an injection of human tetanus immunoglobulin (HTIG) to neutralize the circulating tetanospasmin, to control breathing, and to provide systemic supportive care. Recently, the 500 unit of HTIG is recommended. We report one case of generalized tetanus that was treated with 500 units of HTIG. The patient was discharged without complications.
Key words: Tetanus, Human tetanus immunoglobulin
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