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J Korean Soc Emerg Med > Volume 13(4); 2002 > Article
Journal of The Korean Society of Emergency Medicine 2002;13(4): 593-595.
Antiphospholipid Syndrome Causing a Cerebral Infarction
Jae Min Hur, Sang Kyu Yoon, Young Gi Min, Joon Pil Cho
Department of Emergency Medicine, Ajou University School of Medicine, Suwon, Korea. jpcho@ajou.ac.kr
ABSTRACT
Antiphospholipid syndrome (APS) is a thrombophilic disorder characterized by recurrent abortion, thrombocytopenia, and prolonged activated partial thromboplastin time (aPTT) in which venous or arterial thrombosis, or both, may occur in patients with antiphospholipid antibodies. Antiphospholipid antibodies have been associated with a variety of neurological disorders, many of which, but not all are manifestations of cerebral or ocular ischemia. Recently, we experienced one case of a cerebral infarct due to APS in a 24-year-old female. She visited the emergency department and presented with dizziness and vomiting. After admission, we conducted a physical examination, blood tests, and brain computed tomography. Her blood tests revealed prolonged aPTT and thrombocytopenia, and brain computed tomography showed a right cerebellar and pons infarct. We treated her with anticoagulants. She was discharged with nearly a full recovery on the seventh hospital day.
Key words: Antiphospholipid syndrome, Vertigo, Cerebral Infarction
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