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J Korean Soc Emerg Med > Volume 15(6); 2004 > Article
Journal of The Korean Society of Emergency Medicine 2004;15(6): 580-587.
Aspect and Effect of Sodium Bicarbonate Use in Cardiopulmonary Resuscitation
Hye Young Jang, Yoon Hee Choi, Ju Ok Park, Eun Kyung Eo, Koo Young Jung
1Department of Emergency Medicine, College of Medicine, Ewha Womans University, Seoul, Korea. kyjung@ewha.ac.kr
2Department of Emergency Medicine, Hallym University Sacred Heart Hospital, Seoul, Korea.
Recently, bicarbonate use in cardiopulmonary resuscitation (CPR) has been reappraised in some studies. This study was performed to consider aspects of sodium bicarbonate (SB) use in CPR and to evaluate the effect of SB use in CPR.
In a tertiary university hospital, the CPR records of out-of-hospital cardiac arrest (OHCA) patients over a two-year period were reviewed. First, we examined the cardiac arrest variables, whether SB was used or not, and the time when SB was used. Second, we analyzed the effect of SB use on the CPR outcome.
The study included 187 patients. SB was used in 78 patients (42%). The mean time when SB was used was 16 minutes after initiation of CPR, corresponding to an average 38-minute elapsed time from the patient's collapse. There was no relation between the prehospital arrest time and the SB use rate, but a positive relation was seen between the CPR duration and the SB use rate. The investigation of the effect of SB on CPR outcome included 82 patients, and we performed a logistic regression analysis. SB use seemed to be related to return of spontaneous circulation (ROSC), however, statistically, it was not significant (OR=2.499, 95% CI: 0.491, 12.718).
SB use for OHCA patient resuscitation was not based on consideration of prehospital hypoxia time. SB use did not affect ROSC in this retrospective study.
Key words: Sodium bicarbonate, Cardiac arrest, Cardiopulmonary resuscitation
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