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Journal of The Korean Society of Emergency Medicine 1995;6(1): 122-131. |
| CLINICAL SIGNIFICANCE OF QUALITATIVE TEST FOR DETECTION OF URINARY PARAQUAT BY SODIUM DITHIONITE |
| Sun Man Kim1, Sung Oh Hwang1, Kyung Soo Lim1, Young Sik Kim1, Boo Soo Lee1, Kang Hyun Lee1, Jin Woong Lee1, Deok Woo Park2, Kap Jun Yoon2, Moo Eob Ahn3 |
1Department of Emergency Medicine, Wonju College of Medicine, Wonju, Korea
2Department of Clinical Pathology, Wonju College of Medicine, Wonju, Korea
3Department of Emergency Medicine, Hanlim College of Medicine, Chuncheon, Korea |
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Published online: June 30, 1995. |
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| ABSTRACT |
Background
Mortality from paraquat intoxication depends upon plasma paraquat concentration. To know the severity of paraquat intoxication is important for directing therapeutic modality and predicting prognosis. Sodium dithionite test for urinary paraquat provides an easy and simple method to determine the severity of paraquat intoxication in emergency department.
purpose : To determine whether the result urinary paraquat test by sodium dithionite can predict outcome in patients with paraquat intoxication in emergency department.
Subjects : 48 patients(male 31, female 17, mean age 37 years) who had exposure to paraquat and presented within 24 hours after exposure.
Result : Thirty five patients were positive in paraquat urine test and thirteen patients were negative. Clinical manifestations were more severe in positive patients than in negatives. Complication was much more in positives than in negatives. 28 of 35 patients(80%) in positives and 2 of 13 patients(15%) in negatives died.
Conclusion
Positive test for urinary paraquat is associated with high mortality and morbidity from paraquat intoxication, and qualitative test for urinary paraquat by sodium dithionite is an useful method to determine the severity of paraquat intoxication in emergency department. |
| Key words:
Sodium Dithionite Urine Test, Paraquat Intoxication |
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