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J Korean Soc Emerg Med > Volume 27(1); 2016 > Article
Journal of The Korean Society of Emergency Medicine 2016;27(1): 61-68.
Blood Lipid Profile as a Prognostic Factor in Patients with Organophosphate Poisoning
Dae Geun Han, Dong Hwan Kim, Yong Jin Park
Department of Emergency Medicine, School of Medicine, Chosun University, Gwangju, Korea
Correspondence  Yong Jin Park ,Tel: 062) 220-3285, Fax: 062) 224-3501, Email: chosunem@naver.com,
Received: September 5, 2015; Revised: September 8, 2015   Accepted: October 26, 2015.  Published online: February 29, 2016.
ABSTRACT
Purpose:
The purpose of this study is to compare clinical outcomes with blood lipids level and lipid solubility of organophosphate-poisoned patients.
Method:
Data from 88 patients who visited the emergency room from January 2008 to July 2014 were analyzed. This study was conducted retrospectively using blood test results and progress notes. The contents of data included the type of organophosphate herbicide, ingesting dose, vital signs on emergency room, blood lipids level, electrocardiographic finding, and hospital course. For lipid solubility, octanol/water coefficient was used.
Results:
Among a total of 88 patients with organophosphate herbicide intoxication, 48 patients ingested high lipophilic organophosphate. There were statistically significant between cholesterol and duration of ventilator care. And there was a trend toward significance between cholesterol and intensive care unit, total admission stay, between triglyceride and total admission stay. As cholesterol and triglyceride level of patient was higher, the prognosis was worse.
Conclusion:
In this study, blood cholesterol and triglyceride levels in high lipophilic organophosphate herbicide intoxicated patients are useful predictable factors for prognosis.
Key words: Organophosphate poisoning, Cholesterol, Triglyceride, Prognosis
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